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DNA Making Protein/Mutations
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The Mandella Environment

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Monday: B Day

Aim: How does DNA direct the making of proteins in cells?

Do Now: Draw and label these parts of a cell: cell membrane, nucleus, chromosomes, ribosomes. Of these parts which part makes proteins?

Procedure: Students will draw a huge cell in their notebooks for the do now. This will serve as a review as well as a backdrop for the RNA lesson. Explain how DNA is located in the nucleus and the ribosomes are in the cytoplasm: THEY ARAE NOT IN THE NUCLEUS. Ask: SO how DNA gets to the ribosomes so they can make the proteins? The HELPER MOLECULE IS RNA. (ribonucleis acid) RNA is a chemical that acts as a messenger for DNA.  This is the worktable where protiens are made. RNA carries the coded DNA message from the nucleus to the ribosomes. The ribosome is the worktable for making proteins. The message carried from the ribosome by mRNA (messenger RNA) must be decoded.  DNA is written in one language, AT GC while the protein is written in a different language.  tRNA (transfer RNA translates the DNA code into the code used to make the protein.  rRNA (ribosomal RNA) directs the forming of the protein. The genetic code translates the DNA language into the protein language. Use the conversion chart to explain this process. GIVE to students:  DNA--> mRNA -->tRNA  -- >rRNA  -->Protein -- THIS IS THE FLOW OF INFORMATION WITHIN A CELL. The order of bases in the coded messafe of DNA controls what type of proetins are made. This determines what type of traits you have.  DNA code is chopped into short segments of three code letters. Begin working on Lab 19: Making Proteins: How does DNA make proteins (28-2) T

Homework #14: Complete the study guide worksheet about the DNA molecule.

Tuesday: No students Supetintendent's Conference Day

Aim:

Procedure:

Wednesday: A Day Happy St. Patrick's Day

Aim: How does DNA control the making of proteins?

Do Now: Get your lab folders and finish the lab today.

Procedure: Students will follow the directions that are included in Lab 28-2. THis lab must be completed and handed in for a grade today.

Homework #No Homework tonight

Thursday: B Day

Aim: How does DNA copy itself?

Do Now: What are the jobs of DNA?

Procedure: DNA carries genetic messages for all living things. DNA controls the making of proteins. What has to happen to the chromosomes before mitosis and meisois takes place? Chromosomes have to make a copy of themselves. What are the chromosomes made of? DNA. So how does DNA make a copy of itself? There are four steps to this process.  Use the laddre model to simplify process. Hand out a worksheet and use the overhead to help students visualize this process.  Give students this portion of a DNA molecule and ask them to sequence the steps that take place during copying. A-T, T-A, C-G, C-G, G-C, A-T. 

Homework #15: Complete the study guide worksheet 165 Questions 10 and 11.

Friday: A Day

Aim: What happens when the genetic message changes?

Do Now: Write the genetic code for normal red blood cells and then the genetic code for sickle cell anemia. Ask the students where the genetic code differs? IS this a genetic disorder?

Procedure: Mutation: Any change in the copying of the DNA message. Show students pictures of genetic mutations that are visable in a persons phenotype. Explain that many genetic defects can be internal.  Explore a problem using the internet and the Epson projector about the SLooze Worm....Solve problems such as how doe s genetic mutation occur? Do environmental factors cause mutations?  How do mutations occur is located at http://gslc.genetics.utah.edu/units/disorders/sloozeworm/.

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